James C, Park SY, Chan M, Khajoueinejad N, Alabi D, Lee J, Lantis JC 2nd. The Role of Intermittent Pneumatic Compression in the Treatment of Lower Extremity Chronic Wounds. Surg Technol Int. 2021 May 20;38:79-86. doi: 10.52198/21.STI.38.WH1417. PMID: 33765323. This clinical study reports that Lympha Press intermittent pneumatic compression, used alongside multilayer compression therapy, was associated with smaller wound size, reduced leg circumference, and improved symptoms in patients with chronic lower-extremity wounds related to venous and/or lymphatic disease.

This clinical study looked at 10 patients with long-standing severe venous insufficiency and active lower-leg ulcers that had not improved with multilayer compression alone. These patients had chronic wounds linked to venous and/or lymphatic disease, sometimes described as “lymphophlebitic” disease. The treatment added Lympha Press® intermittent pneumatic compression to their existing wound-care plan. Patients used the device daily for 75 minutes at a minimum of 40 mmHg, while also continuing three-layer compression therapy. Their wounds, leg circumference, pain, and treatment tolerance were monitored weekly over 8 weeks. The study reported that after one week, most patients had decreased leg circumference. and over the eight-week course of treatment patients had meaningful decreases in wound size, with most wounds healing completely. Patients also reported less wound drainage, odor, and pain after continued use. Importantly, there were no reported discomfort issues with Lympha Press® use, and most patients enjoyed using the device. The findings suggest that intermittent pneumatic compression may be a helpful addition to wound care for patients with chronic lower-extremity wounds, especially when swelling and poor venous or lymphatic flow are contributing factors.